Every BioStem product is processed with the utmost care to support the application in Surgical Wounds.

Our innovative technology can preserve the structural integrity and molecular components of fresh tissue.

EXPLORE OUR ADVANCED SURGICAL CARE BRAND:


The market-first cryopreserved human Amniotic
Membrane (AM) derived from Umbilical Cord (UC).


Thinner cryopreserved version of our version of our human Amniotic Membrane.

ADDRESSING SURGICAL RECOVERY:

The normal healing cascade in surgical care is similar to that of wound healing. What makes surgical care unique is that it is an intentional wound in a controlled environment. Disruptions in the normal wound healing cascade can occur with internal surgical cuts (injuries) or strains on tendons and ligaments as well as the external surgical approach incision or wound. Protecting these environments can help improve patient outcomes.

  • Tseng SCG. HC‑HA/PTX3 purified from amniotic membrane as a novel regenerative matrix: insight into relationship between inflammation and regeneration. Invest Ophthalmol Vis Sci. 2016;57(5):ORSFh1‑ORSFh8.
  • Bemenderfer T, Anderson R, Odum S, et al. Effects of cryopreserved amniotic membrane–umbilical cord allograft on total ankle arthroplasty wound healing. J Foot Ankle Surg.2019;58(1):97‑102.
  • DeMill SL, Granata JD, McAlister JE, et al. Safety analysis of cryopreserved amniotic membrane/umbilical cord tissue in foot and ankle surgery: a consecutive case series of 124 patients. Surg Technol Int. 2014;25:257‑261.
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  • Penner M, Younger A, Wing K, et al. Arthroscopic repair of talar osteochondral defects with umbilical cord allograft: a prospective, single‑center, pilot study. Foot Ankle Spec. 2021;14(3):193‑200.
  • Anderson DG, Popov V, Raines AL, et al. Cryopreserved amniotic membrane improves clinical outcomes following microdiscectomy. Clin Spine Surg. 2017;30(9):413‑418.
  • Warner M, Lasyone L. An open‑label, single‑center, retrospective study of cryopreserved amniotic membrane and umbilical cord tissue as an adjunct for foot and ankle surgery. Surg Technol Int. 2014;25:251‑255.
  • Covell DJ, Cohen B, Ellington JK, et al. The use of cryo‑preserved umbilical cord plus amniotic membrane tissues in the resection of tarsal coalition. Foot & Ankle Orthopaedics. 2016;1(1):2473011416S00311.
  • Galli SH, Ferguson CM, David WH, et al. Cheilectomy with or without cryopreserved amniotic membrane–umbilical cord allograft for hallux rigidus.Foot Ankle Orthop. 2021;6(1):2473011420967999.
  • Papanna R, Fletcher S, Moise KJ Jr, et al. Cryopreserved human umbilical cord for in utero myeloschisis repair. Obstet Gynecol. 2016;128(2):325‑330.
  • Cooke M, Tan EK, Mandrycky C, et al. Comparison of cryopreserved amniotic membrane and umbilical cord tissue with dehydrated amniotic membrane/chorion tissue. J Wound Care. 2014;23(10):465‑474, 476.

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